This giant club-cum-music venue-cum-restaurant sits in an atmospheric century-old ports building, with high ceilings and vast windows. But this is no sweaty former industrial building designed to maintain a shabby-chic nod to its past. Since its opening near the beginning of the millennium, Panama has been a slickly polished operation, and very quickly established itself as a major force in Amsterdam’s clubland. The restaurant and bar area is slickly presented, as is the pleasant terrace. The modern European food is passable, but the cocktails and wines are better. The main attraction for most, though, is the club, a vast space with cosy lounge seating dotted about its sides and mezzanine. The music is uniformly house, but the venues size and reputation means it can regularly attract big names. Worth a trip to the newly developed waterfront.